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Name an American cultural breakthrough and chances are good it happened in Harlem. This neighborhood survived flappers and gangsters in the 1920s, booed almost everyone offstage at the Apollo except Ella Fitzgerald, Jimi Hendrix and Michael Jackson, and revolutionized America from Marcus Garvey to Malcom X. See the writing on the wall at the Graffiti Wall of Fame at 106th and Park, then head over to the Studio Museum to watch African American artists change art history. Harlem launched jazz and hip hop and taught Madonna how to vogue, so expect big nights out. Get schooled at the Jazz Museum in Harlem before jazz sets at historic art deco Lenox Lounge. Hit Shrine for slick beats and reggae, and end up at Ginny's Supper Club for soul food with a side of blues. For the morning after, Amy Ruth's serves the Reverend Al Sharpton special: chicken and waffles, gravy optional. East Harlem is largely Latino, and known as El Barrio. The pride of the neighborhood is El Museo del Barrio, a small space packed with contemporary Caribbean and Latin art and encounters with such notables as Nobel Prize winning poet Derek Walcott.

Hipmunk's Best Hotels near Harlem

Soho Grand Hotel
Soho Grand Hotel
|
8.5
Excellent
310 W Broadway, New York
from $167
Conrad New York, NY
Conrad New York, NY
|
9.2
Excellent
102 North End Avenue, New York
from $229
DoubleTree by Hilton New York City - Financial District
from $137
The Hotel @ Fifth Avenue
The Hotel @ Fifth Avenue
|
8.0
Excellent
17 West 32nd St, New York
from $134
The Westin New York Grand Central
The Westin New York Grand Central
|
8.2
Excellent
212 East 42nd Street, New York
from $159
Club Quarters, Times Square - Midtown
Club Quarters, Times Square - Midtown
|
8.5
Excellent
40 W 45th St, New York
from $121
Sheraton New York Times Square Hotel
Sheraton New York Times Square Hotel
|
8.0
Excellent
811 7th Avenue 53rd Street, New York
from $167
Hotel Americano
Hotel Americano
|
7.7
Good
518 West 27th Street, New York
from $145
Grand Hyatt New York
Grand Hyatt New York
|
7.9
Good
109 East 42nd St, NEW YORK
from $160
Refinery Hotel
Refinery Hotel
|
8.9
Excellent
63 W 38th St, New York
from $185