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Name an American cultural breakthrough and chances are good it happened in Harlem. This neighborhood survived flappers and gangsters in the 1920s, booed almost everyone offstage at the Apollo except Ella Fitzgerald, Jimi Hendrix and Michael Jackson, and revolutionized America from Marcus Garvey to Malcom X. See the writing on the wall at the Graffiti Wall of Fame at 106th and Park, then head over to the Studio Museum to watch African American artists change art history. Harlem launched jazz and hip hop and taught Madonna how to vogue, so expect big nights out. Get schooled at the Jazz Museum in Harlem before jazz sets at historic art deco Lenox Lounge. Hit Shrine for slick beats and reggae, and end up at Ginny's Supper Club for soul food with a side of blues. For the morning after, Amy Ruth's serves the Reverend Al Sharpton special: chicken and waffles, gravy optional. East Harlem is largely Latino, and known as El Barrio. The pride of the neighborhood is El Museo del Barrio, a small space packed with contemporary Caribbean and Latin art and encounters with such notables as Nobel Prize winning poet Derek Walcott.

Hipmunk's Best Hotels near Harlem

Kimpton Ink48 Hotel
Kimpton Ink48 Hotel
|
8.4
Excellent
653 11th Avenue, New York
from $119
Iberostar 70 Park Avenue
Iberostar 70 Park Avenue
|
8.5
Excellent
70 Park Ave, New York
from $161
Sheraton Tribeca New York Hotel
Sheraton Tribeca New York Hotel
|
8.3
Excellent
370 Canal Street, New York
from $93
Intercontinental Hotels New York Barclay
Intercontinental Hotels New York Barclay
|
8.6
Excellent
111 East 48th St, New York
from $221
OYO Times Square
OYO Times Square
|
7.0
Good
157 West 47th Street, New York
from $85
Shelburne Hotel & Suites by Affinia
Shelburne Hotel & Suites by Affinia
|
8.3
Excellent
303 Lexington Avenue, New York
from $132
Parker New York, A Hyatt Affiliate Property
Parker New York, A Hyatt Affiliate Property
|
8.0
Excellent
119 West 56th Street, New York
from $146
The Roosevelt Hotel, New York City
The Roosevelt Hotel, New York City
|
7.0
Good
45 E 45th Street, New York
from $97
Millennium Premier New York Times Square
Millennium Premier New York Times Square
|
8.0
Excellent
133 W 44th St, New York
from $132
Hilton Garden Inn Times Square
Hilton Garden Inn Times Square
|
8.4
Excellent
790 Eighth Ave., New York
from $104