Chic and luxurious, the Gran Melia Rome in Vatican combines contemporary cool with a classical twist. The hotel’s façade mimics a palatial Italian villa, and the rooms don’t disappoint. The 116 rooms of Gran Melia Rome are appointed with fine linens and pillows, plush bathrobes, iPod docks, and personal espresso makers. Each room is soundproofed to provide privacy and ensure a restful night’s sleep. Other creature comforts at Gran Melia Rome include a pool and poolside lounge, restaurant, café, and health club. Within walking distance are the Pantheon, Castel Sant’Angelo, and Piazza San Pietro. If you’re looking to explore beyond the immediate area, two rail stations are a quick walk away.